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Incorporate a recognized amount of the antidepressant protriptyline, which serves as an inside regular, to each serum sample and to every external conventional. To remove matrix interferents, move a 0.five-mL aliquot of each serum sample or standard by way of a C18 reliable-stage extraction cartridge. Immediately after washing the cartridge to elim
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POTS also entails neurocirculatory abnormalities throughout supine rest. These consist of fairly speedy mean heart costs and improved NE, DA, and EPI concentrations and elevated cardiac NE spillover [forty, 44, fifty two], indicating amplified sympathetically mediated exocytosis and adrenomedullary hormonal system activation in POTS patients even w